SEVOflurane Inhalation in CARdiac Arrest Resuscitated Patients Treated With Therapeutic Hypothermia

SEVOflurane Inhalation in CARdiac Arrest Resuscitated Patients Treated With Therapeutic Hypothermia

Studying the feasibility of an initial sedation with inhalated sevoflurane during therapeutic hypothermia of cardiac arrests resuscitated patients.

Prospective clinical study in ICU with ventilated patients sedated with sevoflurane using the Mirus® and Anaconda® , establishing the feasibility of an initial sedation of patients resuscitated from cardiac arrest and treated with therapeutic hypothermia.

Inclusion Criteria:

• -Adult patients ventilated requiring therapeutic hypothermia in ICU
• Stable respiratory and hemodynamic conditions
• Epinephrine and norepinephrine infusion rate < 1,5 g/kg/min
• Consent of patients or family
• Arterial line
• Patients resuscitated after cardiac arrest
• No Flow < 10 min
• Low Flow < 20 min
• Neutropenia < 1 G/L
• Post traumatic cardiac arrest
• Contraindication of halogenated anesthesics
• Extra corporeal life support or intra aortic balloon pump

Exclusion Criteria:

• -Pregnant woman
• Hemodynamic instability
• Brain death defined by the disappearance of brain stem reflexes