Acute Effects of Natural and Interesterified Fats-margarine on Lipemic and Insulinemic Response

Acute Effects of Natural and Interesterified Fats-formulated Margarine on Lipemic and Insulinemic Response

Interesterified (IE) fat blends will respond differently in terms of postprandial lipemia and insulinemic responses compare to a trans free palm margarine (TFPM).

The objective of this study was to investigate whether IE-fat blends behave differently on postprandial serum lipid, insulin, C-peptide and glucose concentration compare to TFPM. A randomised, double-blind crossover (3 × 3 arms) orthogonal Latin-square design was used and conducted on 10 males and 10 females adults. During postprandial challenge day, each subject received an a test muffin incorporated with test margarine. Blood samples were collected at half-hourly intervals until 4 hr by using cannulation technique.

Inclusion Criteria:

• Body Mass Index (BMI) between 18.5 and 24.9
• <130mmHg for systolic pressure and <80 mmHg for diastolic pressure
• Blood glucose level in the range of 3.9 to 5.5 mmol/L
• Total cholesterol less than 5.17 mmol/L
• No use of tobacco and no consumption of alcohol.

Exclusion Criteria:

• Suffer from chronic disease
• Metabolic syndrome
• Consuming any medical prescriptions
• People with blood clotting problem
• Women who are pregnant
• Hypertensive person