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The purpose of this study is to determine whether grapefruit juice alters the metabolism of cortisol following intense exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Grapefruit juice | Experimental | 12.5 OZ Grapefruit juice: Subject will ingest grapefruit juice 12.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon prior to their evening visit |
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| Apple juice | Placebo Comparator | 10.5 OZ Apple juice: Subject will ingest apple juice 10.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon 3 hours prior to their evening visit. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Grapefruit juice | Other | Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma cortisol change from baseline at 45 minutes | Plasma cortisol levels will be collected at baseline and 45 minutes post-exercise for the Grapefruit visit intervention and for the Apple juice intervention. The interventions are acute ( 1 day), there is no follow up. The interventions are at least 1 week apart. For a given subject, the estimated time for study completion for the 2 treatments is 14 to 30 days. | Baseline, 45 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Change in plasma cortisol from 15 minutes to baseline | Plasma cortisol levels will be collected at baseline and 15 minutes post-exercise for the Grapefruit visit intervention and for the Apple juice intervention. The interventions are acute ( 1 day), there is no follow up. The interventions are at least 1 week apart. For a given subject, the estimated time for study completion for the 2 treatments is 14 to 30 days. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pedro Del Corral, PhD/MD | Contact | 630 8296575 | pdelcorral@ben.edu |
| Name | Affiliation | Role |
|---|---|---|
| Pedro Del Corral, PhD-MD | Benedictine University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Benedictine University | Recruiting | Lisle | Illinois | 60532 | United States |
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| Apple juice | Other | Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice or Apple juice ingested in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only |
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| baseline, 15 minutes |