Clinical, Physiological and Prognostic Implication of Microvascular Status

Clinical, Physiological and Prognostic Implication of Index of Microcirculatory Resistance

There are several physiologic parameters in evaluating cardiovascular disease. This study will reveal which parameter is the most proper value in predicting disease severity and risk factors of patients.

Fractional Flow Reserve (FFR), index of microcirculatory resistance (IMR), and coronary flow reserve (CFR) will be measured in stable angina patients before coronary intervention.

Relationship between angiographic characteristics of patients and FFR, IMR, CFR will be analyzed. Comparison of risk factors and prognosis between parameters will be also analyzed. This study will evaluate that which parameter is correlate with disease severity and risk factors of patients.

Inclusion Criteria:

• Age ≥ 18
• Patients with stable angina
• FFR, IMR, CFR were measured before coronary intervention

Exclusion Criteria:

• Patients who have severe side effects or contraindication to hyperemic agents (ex. adenosine)
• Patients with hemodynamic instability
• elevation of cardiac enzymes, evidence of acute MI, or a culprit vessel of acute coronary syndrome