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With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.
All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for ~5.75 h while the participants were in the lab.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No exercise | Experimental | participants will remain sedentary during testing |
|
| Meal then exercise | Experimental | 45 min of resistance training will be performed after a standard meal |
|
| exercise then meal | Experimental | 45 min of resistance training will be performed prior to a standard meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No exercise | Other | During the no exercise trial (NoEX), the participants will remain sedentary during testing. |
|
| Measure | Description | Time Frame |
|---|---|---|
| glucose concentrations | Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h |
| Measure | Description | Time Frame |
|---|---|---|
| triglyceride concentrations | Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h |
| Measure | Description | Time Frame |
|---|---|---|
| GLP-1 concentrations | Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h |
Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28970202 | Derived | Heden TD, Liu Y, Kanaley JA. A comparison of adipose tissue interstitial glucose and venous blood glucose during postprandial resistance exercise in patients with type 2 diabetes. J Appl Physiol (1985). 2018 Apr 1;124(4):1054-1061. doi: 10.1152/japplphysiol.00475.2017. Epub 2017 Sep 28. |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Meal then exercise | Other | During the post-meal exercise trial (M→EX), 45 min of resistance training will be performed |
|
|
| exercise then meal | Other | During the exercise prior to the meal trial (EX→M), 45 min of resistance training will be performed |
|
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| D004700 | Endocrine System Diseases |