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Cognitive and memory problems characterize Alzheimer's disease (AD). Along with these disorders, psychological and behavioral symptoms (also known as neuropsychiatric symptoms) , as well as pathophysiological processes are frequently found and involved significantly in maintaining autonomy, prognosis and treatment of the disease. Apathy or disorder motivation is the most common disorder behavior and early stages of cognitive impairment. Apathy is particularly associated with cognitive difficulties such as attention deficit disorder - concentration.
In terms of prevention as term care , there is now a broad consensus that interventions on cognition and behavior must not be limited to pharmacological treatment but should also promote non-drug approaches.
Interest in video games (serious games and serious games) as intervention support rehabilitation is growing. Similarly, the virtual reality (VR) and the new information technologies and communications offer significant opportunities in terms of rehabilitation and therapeutic assistance.
This protocol is part of a European project to propose techniques for improving the treatment of people at risk of social exclusion ( VERVE project ) aims .
A first experiment conducted in 2013 showed the acceptability of Virtual Reality (VR) in healthy elderly subjects. In a second step , it is important to validate the feasibility of using the RV or in frail subjects with mild cognitive impairment or Alzheimer's disease in mild to moderate in a clinical environment.
This is a biomedical , randomized given to a group of patients with mild cognitive impairment or Alzheimer's disease & diseases associated with mild to moderate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Condition virtual reality (VR) | Experimental | The subject is placed in front of a Barcotm screen capable of displaying high quality images. |
|
| Condition classic cognitive stimulation (CSC) | Active Comparator | It is proposed about using the test dam Zazzo suitable for elderly. This classic test measures sustained attention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Condition virtual reality (VR) then Condition classic cognitive stimulation (CCS) | Other |
| ||
| Condition classic cognitive stimulation (CCS) then Condition virtual reality (VR) |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluate the acceptability of the RV | Analog scale assessment of satisfaction from 0 to 100% is given at the end of experience about that evaluates:
| At the end of experience (45 min) |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluate the motivation of subjects (interest, cognition) is greater in the virtual environment during the VR experience compared to a conventional cognitive stimulation activity (CSC). |
|
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Inclusion Criteria:
Male or female age ≥ 60 years.
Introducing either:
Subject undisturbed locomotion requiring the use of a walking aid.
Score at the Mini Mental Test (MMSE) between 16 and 28.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Philippe ROBERT, PUPH | Centre Hospitalier Universitaire de Nice | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut Claude Pompidou | Nice | 06000 | France |
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| Other |
|
| At the end of experience (45 min) |
| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D024801 | Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D003072 | Cognition Disorders |
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