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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alendronate | Experimental | 1% Alendronate gel once in periodontal pocket (Gums) |
|
| Placebo | Placebo Comparator | Placebo gel once in periodontal pocket (Gums) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alendronate | Drug |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline plaque scores at 2 month and 6 month | Plaque scores assessed at baseline, at 2 months and 6 months for Alendronate and placebo group | At baseline, 2nd month and 6th month |
| Change from baseline gingival scores at 2 month and 6 month | Gingival scores assessed at baseline, at 2 months and 6 months for Alendronate and placebo group | At baseline, 2nd month and 6th month |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline Probing depth at 2 month and 6 month | Probing depth assessed at baseline, at 2 months and 6 months for Alendronate and placebo group | At baseline, 2nd month and 6th month |
| Change from baseline Periodontal attachment level at 2 month and 6 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dr. Anuj Sharma, BDS, MDS | RIMS, Ranchi | Principal Investigator |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 6, 2016 | |
| Reset | Mar 4, 2016 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 6, 2016 | Mar 4, 2016 |
| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D019386 | Alendronate |
| ID | Term |
|---|---|
| D004164 | Diphosphonates |
| D063065 | Organophosphonates |
| D009943 | Organophosphorus Compounds |
| D009930 | Organic Chemicals |
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|
Periodontal attachment level assessed at baseline, at 2 months and 6 months for Alendronate and placebo group |
| At baseline, 2nd month and 6th month |
| Change from baseline intrabony defect depth at 6 month | intrabony defect depth assessed at baseline and 6 months for Alendronate and placebo group | At baseline and 6th month |
| D002908 |
| Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |