Observational Study on Patients With Chronic Hepatitis B

A Retrospective-prospective Observational Study to Evaluate the Effect of Anti-viral Treatment on the Long-term Outcome in Patients With Chronic Hepatitis B (SEARCH-B Study)

The study was conducted to evaluate the effect of anti-viral treatment on long-term outcome on patients with chronic hepatitis B.

Inclusion Criteria:

• Male or female, aged over 30 (inclusive) years of old
• Patients has a history of diagnosis of chronic hepatitis B (ie. HBsAg positive for more than 6 months)
• For patients with HBsAg positive, patients should be undergoing anti-viral treatment
• For patients with HBsAg negative, a documented evidence of previous anti-viral treatment should be provided.
• Life expectancy is more than 1 year
• Good treatment compliance.

Exclusion Criteria:

• Patients has a history of diagnosis of hepatocellular carcinoma
• Patients with Child Pugh C
• Coinfected with HCV, HDV and HIV
• Suffering from other serious disease
• Taking part in other clinical trial