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The purpose of this study is to determine whether BRAND'S® Essence of Chicken are effective in the promotion of resilience and resistance to stress-associated cognitive inhibition.
This is a placebo-controlled, randomized, double-blind trial. There will be 100 subjects. Subjects are randomly assigned into either placebo or BRAND'S® Essence of Chicken (BEC), 70cc daily for 2 weeks, group.
Stress test, cognitive function assessment and blood tests will be carried out at Week 0, Week 2, and Week 4 (2 weeks after termination of supplementation).
The primary end-point is the better improvement of cognitive function after supplement with BEC than placebo. The second endpoints include improvement of global health survey and changes of biomarkers related to stress and immunity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| placebo | Placebo Comparator | placebo with the same color, order, taste as BRAND'S® Essence of Chicken , 70cc daily for 2weeks |
|
| Chicken Essence | Experimental | BRAND'S® Chicken Essence 70cc, daily for 2 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chicken Essence | Dietary Supplement | BRAND'S® Chicken Essence of 70cc daily for 2 weeks Placebo 70 cc daily for 2 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in cognitive function at week 2 and week 4 | Working memory, Episodic memory, Attention | baseline, week 2, week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in biomarkers and and immunity related to stress at week 2 and week 4 | ACTH, Cortisol, Melatonin, Glucose, BUN/CRE, GOT/GPT | baseline, week 2, week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in global health survey at week 2 and week 4 | chinese version of SF36 | baseline, week 2, week 4 |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ming-Show Hsieh, R.N. | Contact | 886-2-22490088 | 8112 | 13508@s.tmu.edu.tw |
| Chaur-Jong Hu, M.D. | Contact | 886-2-22490088 | 8112 | chaurjongh@tmu.edu.tw |
| Name | Affiliation | Role |
|---|---|---|
| Chaur-Jong Hu, M.D. | Neurology, Shuang Ho Hospital, Taipei Meidcal University, New Taipei City, Taiwan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shuang Ho Hospital, Taipei medical University | Recruiting | New Taipei City | Taiwan |
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