Effect of Periodontal Treatment on Salivary Biomarkers

Effect of Periodontal Treatment on Salivary Biomarkers.

The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis.

treatment will include 4 - 6 sessions of scaling + root planning, oral hygiene instructions and motivation.

Whole saliva will be collected at intake and 8 - 14 weeks post periodontal treatment.

Saliva will be analyzed for trans locator protein. Study hypothesis: Periodontal treatment has an affect on saliva components.

Inclusion Criteria:

• healthy patients
• moderate - sever chronic periodontitis

Exclusion Criteria:

• systemic disease
• pregnancy
• subjects under the age of 18