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The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis.
treatment will include 4 - 6 sessions of scaling + root planning, oral hygiene instructions and motivation.
Whole saliva will be collected at intake and 8 - 14 weeks post periodontal treatment.
Saliva will be analyzed for trans locator protein. Study hypothesis: Periodontal treatment has an affect on saliva components.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| periodontal treatmnent | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| periodontal treatment - scaling and root planning | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Whole saliva & translocator protein (TSPO) | Change in whole saliva & translocator protein (TSPO) post periodontal treatment | Intake of patients than 8 - 12 weeks after periodontal treatment (scaling & root planning) |
| Measure | Description | Time Frame |
|---|---|---|
| Periodontal measurements (periodontal pocket depth, bleeding on probing & clinical attachment level) | periodontal probing depth, bleeding on probing and clinical attachment level. | Intake 8 - 12 weeks post periodontal treatment (scaling & root planning) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eran Front, DMD | Contact | +97246652254 | efront@poria.health.gov.il |
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| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| D002908 |
| Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |