RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo

Randomized Controlled Trial Comparing Post-VATS Analgesia Between Patients With an Intrathecal Injection of Morphine and Sufentanil Versus Placebo.

The purpose of the study is to determine if the administration of a mix of Sufentanil and Morphine in intrathecal is a better analgesia regimen than PCA alone in patient post-VATS.

This study will compare the need for analgesia (Hydromorphone PCA) of two groups of patients post-VATS. The placebo group will only have a PCA for post-operative analgesia, witch is the standard care for patient post-VATS. The experimental group will have a intrathecal injection of a mix of morphine and sufentanil before the induction of anesthesia.

Inclusion Criteria:

• VATS
• ASA 1,2 or 3
• Minimum weight of 50 kg
• Patient able to consent

Exclusion Criteria:

• Patient refusal
• Patient unable to understand PCA
• Contraindication to rachianalgesia
• Zona
• Pregnancy
• Over 30 mg of morphine during the last 24 hours
• Use of Pregabalin, Gabapentin, Doluxetin, Amitriptyline or NSAI in a context of chronic pain
• Severe allergic reaction to morphine, hydromorphone, sufentanil or local anesthetic
• Intubation over 1 hour after surgery (unability to use PCA)
• High risk of conversion to thoracotomy
• Unable to perform rachianalgesia due to technical difficulties