Testing Effect and Schizophrenia | NCT02150174 | Trialant

Testing Effect and Schizophrenia | NCT02150174 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Patients with schizophrenia	Experimental		Behavioral: Retrieval practice effect using word pairs and cued recall tests with feedback
Healthy subjects	Active Comparator		Behavioral: Retrieval practice effect using word pairs and cued recall tests with feedback

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Retrieval practice effect using word pairs and cued recall tests with feedback	Behavioral	In the first phase (encoding), people study a list of 48 word pairs non semantically associated. Then (initial test), they recall half of word pairs or restudy the other half. In the second phase (final test) which takes place 2 days later, they recall all the 48 the word pairs.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Number of word pairs properly recalled	- The aim is to investigate the retrieval practice effect using word pairs and cued recall tests with feedback in patients with schizophrenia and healthy controls. In the first phase (encoding), people study a list of 48 word pairs non semantically associated, then half of the pairs are presented in its completed form for two times, and for the other half the two subsequent re-exposure trials are framed as cued recall tests (the first word is presented and the subject has to remember and give orally the second word, and a feedback is given). In the second phase (final test) which takes place 2 days later, all the 48 word pairs are presented as a cued recall test. - We will compare in patients with schizophrenia and healthy controls final performance recall for information studied and recalled ("test" condition) to those for information studied and then re-studied ("re-study" condition).	Final test : 2 days after the first experimental session

Secondary Outcomes

Measure	Description	Time Frame
Difference between final performance recall and memory span score	In each group (patients with schizophrenia and healthy controls) : Difference between the final performance recall (see primary outcome measure) in "test" condition and "re-study" condition AND memory span score.	Final test : 2 days after the first experimental session

Contacts/Locations Module

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
31711448	Result	Jantzi C, Mengin AC, Serfaty D, Bacon E, Elowe J, Severac F, Meyer N, Berna F, Vidailhet P. Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation. BMC Psychiatry. 2019 Nov 11;19(1):355. doi: 10.1186/s12888-019-2341-y.

Condition Browse Module