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| ID | Type | Description | Link |
|---|---|---|---|
| ChuncheonSHH YJH-1 | Other Identifier | ChuncheonSHH |
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Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.
Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.
This study is patient-control setting study. Firstly, from July 2007 through February 2014, all the patients who were performed ERCP will be enrolled. The inclusion criteria is the patients with common bile duct stone. The exclusion criteria is patients with biliary stenosis, PSC, retained GB stone, or who were lost to follow-up. The main outcome is the association between periampullary diverticulum, common bile duct angle, and recurrent CBD stone. This will be evaluated by univariate and multivariate analyses.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with recurrent CBD stone |
| ||
| Patients without recurrent CBD stone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The existence of periampullary diverticulum | Other | Periampullary diverticulum has been postulated as risk factor of recurrent CBD stone. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The association between existence of periampullary diverticulum and recurrent CBD stone | The association between existence of periampullary diverticulum and recurrent CBD stone will be assessed by univariate analysis.(unit of analysis: odds ratio, statistical method: Fisher's exact test) | retrospective (up to 8 years) |
| Measure | Description | Time Frame |
|---|---|---|
| The association between common bile duct angle and existence of recurrent CBD stone | The association between common bile duct angle and recurrent CBD stone will be assessed by univariate analysis (unit of analysis: angle, statistical method: student's t test) | retrospective (up to 8 years) |
| Measure | Description | Time Frame |
|---|---|---|
| The risk factors for the development of recurrent CBD stone | The risk factors for the development of recurrent CBD stone will be assessed by multivariate analysis, based on results of univariate analyses. (statistical method: logistic regression analysis) | retrospective (up to 8 years) |
Inclusion Criteria:
Exclusion Criteria:
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Patients who were diagnosed as CBD stone or calculous cholangitis will be enrolled. These patients will be divided by patienst with recurrent CBD stone (devlopment of CBD stone after 1 year from the first development of CBD stone) or not .
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jai Hoon Yoon, M.D.,Ph.D. | Contact | +821032553957 | jaihoonyoon@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jai Hoon Yoon, M.D..Ph.D. | Hallym University College of Medicine, Chuncheon Sacred Heart hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chuncheon Sacred Heart Hospital | Recruiting | Chuncheon | Gangwon-do | 200704 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16858527 | Background | Keizman D, Shalom MI, Konikoff FM. An angulated common bile duct predisposes to recurrent symptomatic bile duct stones after endoscopic stone extraction. Surg Endosc. 2006 Oct;20(10):1594-9. doi: 10.1007/s00464-005-0656-x. Epub 2006 Jul 20. | |
| 23924499 | Background | Katsinelos P, Chatzimavroudis G, Tziomalos K, Zavos C, Beltsis A, Lazaraki G, Terzoudis S, Kountouras J. Impact of periampullary diverticula on the outcome and fluoroscopy time in endoscopic retrograde cholangiopancreatography. Hepatobiliary Pancreat Dis Int. 2013 Aug;12(4):408-14. doi: 10.1016/s1499-3872(13)60063-6. |
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| ID | Term |
|---|---|
| D004240 | Diverticulum |
| ID | Term |
|---|---|
| D000076385 | Diverticular Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| CBD angle | Other | Narrow CBD angle has been postulated as risk factor for the development of recurrent CBD stone |
|
| 18635174 | Background | Panteris V, Vezakis A, Filippou G, Filippou D, Karamanolis D, Rizos S. Influence of juxtapapillary diverticula on the success or difficulty of cannulation and complication rate. Gastrointest Endosc. 2008 Nov;68(5):903-10. doi: 10.1016/j.gie.2008.03.1092. Epub 2008 Jul 16. |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |