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| ID | Type | Description | Link |
|---|---|---|---|
| Substudy 1 | Other Identifier | Medizinische Klinik 1, University of Erlangen-Nurnberg |
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| Name | Class |
|---|---|
| University of Erlangen-Nürnberg | OTHER |
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The purpose of this study is to determine the effect of 12 weeks of WB-EMS either applicated passive in a supine resting position or active during slight movements compared with a non-training control group on body composition, muscle strength and QoL in patients with ulcerative colitis.
Our main hypothesis is that active WB-EMS application is significantly more favorable to address our primary endpoints compared with passive application.
Our secondary hypothesis is that passive WB-EMS application is significantly more favorable to address our primary endpoints compared with non-training control.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| active WB-EMS | Experimental | 2 sessions/week with 20 min of active WB-EMS application |
|
| Passive WB-EMS | Experimental | 2 sessions/week with 20 min of passive WB-EMS application in a resting supine position |
|
| Inactive Control Group | No Intervention | sedentary non-training control group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| active Whole Body Electromyostimulation | Other |
| ||
| Passive WB-EMS |
| Measure | Description | Time Frame |
|---|---|---|
| Lean Body Mass | Lean Body Mass (LBM) and Appendicular Skeletal Muscle Mass (ASMM) as assessed by Dual-Energy-x-Ray Absorptiometry (DXA) | 12 weeks, baseline to 12 week follow-up |
| Isokinetic muscle strength | Isokinetic muscle strength of the leg extensors and - flexors as assessed by a isokinetic leg strength | 12 weeks, baseline to 12 week follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of Life (QoL) | QoL as assessed by inflammatory bowel disease questionnaire (IBDQ-D) and Depression Scores | 12 weeks, baseline to 12 week follow-up |
| Isometric muscle strength | Isometric strength of the trunk flexors. |
| Measure | Description | Time Frame |
|---|---|---|
| Aerobic capacity | Aerobic capacity as assessed by 6 min walking test | 12 weeks, baseline to 12 weel follow-up |
| Inflammatory Markers | 12 weeks, baseline to 12 week follow-up |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yurdagül Zopf, MD | University of Erlangen-Nürnberg | Study Chair |
| Wolfgang K Kemmler, PhD | University of Erlangen-Nürnberg Medical School | Study Director |
| Michael Weineck, MS | University of Erlangen-Nürnberg | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medizinische Klinik 1, University of Erlangen-Nurnberg | Erlangen | Franconia | 91054 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24130433 | Background | Kemmler W, von Stengel S. Whole-body electromyostimulation as a means to impact muscle mass and abdominal body fat in lean, sedentary, older female adults: subanalysis of the TEST-III trial. Clin Interv Aging. 2013;8:1353-64. doi: 10.2147/CIA.S52337. Epub 2013 Oct 7. | |
| 23949160 | Background | Kemmler W, Bebenek M, Engelke K, von Stengel S. Impact of whole-body electromyostimulation on body composition in elderly women at risk for sarcopenia: the Training and ElectroStimulation Trial (TEST-III). Age (Dordr). 2014 Feb;36(1):395-406. doi: 10.1007/s11357-013-9575-2. Epub 2013 Aug 16. |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| D015212 | Inflammatory Bowel Diseases |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| Other |
|
| WB-EMS application | Device |
|
| 12 weeks, baseline 12 week follow-up |
| D003108 |
| Colonic Diseases |
| D007410 | Intestinal Diseases |