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The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva parameters with array - Comparative Genomic Hybridization (aCGH) results and ongoing pregnancy rates.
The present study was designed to determine if there is a correlation between the Eeva System parameters and aCGH testing results. Embryos will be selected for transfer based on aCGH results and morphology. The Clinical site will have no access to the Eeva analysis at the time of the transfer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IVF patients undergoing aCGH Testing | Women undergoing fresh IVF treatment and array-comparative genomic hybridization testing (aCGH), as recommended based on medical need by the clinical site reproductive endocrinologist. |
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| Measure | Description | Time Frame |
|---|---|---|
| Eeva time-lapse parameters and aCGH testing results | Analysis of correlation between time-lapse parameters collected by the Eeva System and array-Comparative Genomic Hybridization (aCGH) results | 5-6 days |
| Measure | Description | Time Frame |
|---|---|---|
| Embryo Implantation Rate | Correlation of time-lapse parameters collected by Eeva and implantation rate | 6 weeks |
| Clinical Pregnancy Rate | Correlation of time-lapse parameters collected by Eeva and clinical pregnancy rate |
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Inclusion Criteria:
Exclusion Criteria:
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Women undergoing fresh IVF treatment and undergoing aCGH testing, as recommended based on medical need by the clinical site reproductive endocrinologist.
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| Name | Affiliation | Role |
|---|---|---|
| Shehua Shen, MD, ELD | Progyny, Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Main Line Fertility | Bryn Mawr | Pennsylvania | 19010 | United States |
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| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| 6 weeks |
| Ongoing pregnancy rate | Correlation of time-lapse parameters collected by Eeva and ongoing pregnancy rate | 8-12 weeks |