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| ID | Type | Description | Link |
|---|---|---|---|
| TST-1872-p | Other Identifier | Auxogyn |
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The purpose of this postmarket study is to gather data to evaluate the impact of using Eeva with traditional morphology grading on clinical pregnancy rates.
The purpose of this postmarket study is to gather data to evaluate the impact of using Eeva with traditional morphology grading on clinical pregnancy rates, as compared to a matched case control group that used morphology grading only to select embryos for transfer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Eeva Test Group | Day 3 embryo transfers that used Eeva predictions with morphology grading. | ||
| Matched case control group | Day 3 embryo transfers using morphology grading only (from a matched concurrent control group). |
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| Measure | Description | Time Frame |
|---|---|---|
| Rate of clinical pregnancy | To compare the rate of clinical pregnancy at approximately 5-8 weeks gestational age for the Day 3 embryo transfers that used Eeva predictions with morphology grading to that for Day 3 embryo transfers using morphology grading only (from a matched concurrent control group at each clinical site comprised of year 2011-2013 patients). | 5-8 weeks gestational age |
| Measure | Description | Time Frame |
|---|---|---|
| Implantation rate (# of implanted embryos out of # of total embryos transferred) | 5-8 weeks gestational age. | |
| Ongoing Pregnancy Rate (gestational week 10-12) | Gestational age week 10-12 | |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing in vitro fertilization treatment who provide informed consent and plan to undergo Day 3 embryo transfer.
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| Name | Affiliation | Role |
|---|---|---|
| Shehua Shen, MD, ELD | Progyny, Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gent University Hospital | Ghent | East Flanders | 9000 Gent | Belgium | ||
| VU University Medical Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27619774 | Derived | Kieslinger DC, De Gheselle S, Lambalk CB, De Sutter P, Kostelijk EH, Twisk JW, van Rijswijk J, Van den Abbeel E, Vergouw CG. Embryo selection using time-lapse analysis (Early Embryo Viability Assessment) in conjunction with standard morphology: a prospective two-center pilot study. Hum Reprod. 2016 Nov;31(11):2450-2457. doi: 10.1093/humrep/dew207. Epub 2016 Sep 12. |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| Multiple pregnancy rate |
| Gestational weeks 5-8 and 10-12 |
| Spontaneous miscarriage rate | Gestational age week 10-12 |
| Amsterdam |
| South Holland |
| 2500 BH |
| Netherlands |