Sub Lingual Misoprostol Before IUD Insertion in Women With Only Previous Cesarean Section

SUB LINGUAL MISOPROSTOL PRIOR TO IUD INSERTION IN WOMEN WITH ONLY PREVIOUS CESARIAN SECTION: A Randomized Controlled Trial

The aim of the work is to evaluate the efficacy of the sub lingual prostaglandin E1 synthetic analogue (misoprostol) before IUD insertion to facilitate the procedure in patients delivered before only by cesarean section.

The study will be conducted at Ain Shams University Maternity Hospital. 124 women candidate for Cu T 380A IUD insertion will be enrolled in the study. Half of them will receive 400 micro gram of misoprostol (Sigma) sub lingually and the other half will receive the placebo two hours before IUD insertion.

Inclusion Criteria:

• Normal size uterus.
• Willing to participate.
• Candidate for IUD insertion.
• Delivered only by cesarean section.
• Last delivery is more than 40 days before participating in the study.

Exclusion Criteria:

• Previous vaginal delivery
• Signs of genital infection.
• Menopause.
• Body mass index (BMI) > 35 kg/m2.
• Contraindication to misoprostol.
• Copper allergy.
• Positive pregnancy test.
• Had a prior attempt for IUD insertion.
• Uterine anomalies.
• Uterine fibroid.