Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection

Clinical and Microbiological Evaluation of Techniques for Scaling and Root Planing Per Quadrant and One Stage Full Mouth Disinfection Associated With Azithromycin or Chlorhexidine: Randomized Controlled Trial

Evaluate and compare the effectiveness in a clinical and microbial perspective one stage full-mouth disinfection technique in relation to scaling and root planing per quadrant associated with chlorhexidine or azithromycin.

Seventy -seven systemically healthy subjects with chronic periodontitis were randomly included in 6 different predefined groups. The following periodontal parameters were evaluated: probing depth , clinical attachment level , plaque index, gingival index and percentage of areas affected by periodontal disease. Microbiologically were evaluated the bacterial load and specific load of five bacterias: The quantification of the bacteria was performed by real-time Polymerase Chain Reaction . The clinical and microbial baseline evaluations were performed ( periodontal pre- therapy) , 90 and 180 days after treatment.

Inclusion Criteria:

• Diagnosis of slight-moderate chronic periodontitis

Exclusion Criteria:

• Those who were making regular use of antibiotics or anti-inflammatory drugs or had done up to three months before the beginning of the study;
• those who were making regular use (twice a day) of oral rinses with chlorhexidine or essential oils or have made regular use within three months prior to study entry;
• individuals with a history of sensitivity to chlorhexidine or azithromycin;
• subjects undergoing periodontal therapy include dental scaling procedures in the 12 months preceding the start of the study;
• subjects with impaired bifurcation or trifurcation class III;
• who required antibiotic prophylaxis for conducting clinical periodontal examination
• subjects with removable partial dentures and removable or fixed orthodontic appliance.