A Micro/Nano Device for Exhaled Breath Analysis

A Micro/Nano Device for Exhaled Breath Analysis

Use of a microfabricated silicon device to concentrate ultra trace volatile organic compounds (VOCs) in human exhaled breath for quantitative analysis of VOCs.

Will use Fourier Transform Mass Spectrometry (FT-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) to analyze concentrated VOCs. The purpose of this study is to search for disease-related markers in the breath in subjects with known or suspected lung or other cancer, or pulmonary disease.

Inclusion Criteria:

• For controlled (healthy) subjects - we are seeking persons who do not have a known history of cancer or pulmonary disease.
• Both smokers and nonsmokers are invited to participate as control subjects.
• For experimental subjects, we are seeking persons with pulmonary disease but no known history of cancer, as identified by the investigators during routine clinic or office visits.
• Additionally for experimental subjects, we are seeking persons with known or suspected lung or other cancers, as identified by the investigators during routine clinic or office visits.

Exclusion Criteria: