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The purpose of this study is to:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Immediate release capsule | Active Comparator | Immediate release capsule treatment under fasted condition |
|
| sustained release tablet | Experimental | sustained release tablet treatment under fasted condition |
|
| sustained release tablet (high fat meal) | Experimental | sustained release tablet under high fat meal condition. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lyrica | Drug |
| ||
| Experimental drug |
| Measure | Description | Time Frame |
|---|---|---|
| Cmax, AUC of pregabalin | 0~36h |
| Measure | Description | Time Frame |
|---|---|---|
| Safety evaluation | 0~24day |
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Inclusion Criteria:
Exclusion Criteria:
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sustained release formulation of pregabalin |
|
| High fat meal | Dietary Supplement |
|
| fasted | Dietary Supplement |
|
| ID | Term |
|---|---|
| D009437 | Neuralgia |
| ID | Term |
|---|---|
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000069583 | Pregabalin |
| D015507 | Drugs, Investigational |
| ID | Term |
|---|---|
| D005680 | gamma-Aminobutyric Acid |
| D000613 | Aminobutyrates |
| D002087 | Butyrates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D000596 | Amino Acids |
| D000602 | Amino Acids, Peptides, and Proteins |
| D004364 | Pharmaceutical Preparations |
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