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The purpose of this study is to compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2) while multiple dosing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Immediate release capsule(lyrica capsule 150mg) | Active Comparator | Immediate release capsule repeat treatment for 3days under fasted condition |
|
| sustained release tablet | Experimental | sustained release tablet repeat treatment for 3days under fasted condition |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate release capsule(lyrica 150mg * 2/day) | Drug | Immediate release capsule |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measure blood concentration of pregabalin | 0~4day / 14~18day |
| Measure | Description | Time Frame |
|---|---|---|
| Safety evaluation | 0~25day |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Catholic medical center | Seoul | Seocho-gu | South Korea |
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| sustained release tablet | Drug | sustained release tablet |
|
| ID | Term |
|---|---|
| D009437 | Neuralgia |
| ID | Term |
|---|---|
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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