A Study to Evaluate Efficacy and Safety of Methacholine Chloride Challenge Test in Diagnosis of Adult Asthma

The purpose of this study is to evaluate efficacy and safety of Methacholine Chloride challenge test in diagnosis of adult asthma

Inclusion Criteria:

• FEV1/forced vital capacity(FVC) must be 70% or more
• <10% decrease in FEV1 in response to inhalation of normal saline

Exclusion Criteria:

• Moderate airflow limitation (FEV1 < 60% predicted or < 1.5 L)
• Heart attack or stroke in last 3 months
• Uncontrolled hypertension, systolic BP>200, or diastolic BP>100