Associations of Exposure to Bisphenol A With Blood Pressure and Epigenetic Change

Associations of Exposure to Bisphenol A With Blood Pressure and Epigenetic Change

• Bisphenol A(BPA) is an endocrine disrupting chemical, which mimics the action of estrogen.
• Previous studies reported that BPA exposure is associated with increased risk of cardiovascular diseases.
• Exposure to BPA occur mainly through oral route, and epoxy coating of canned food is one of the well established source.
• The investigators hypothesis is that increased BPA exposure from canned beverage would disrupt normal physiology in a short term.
• In the present trial the investigators are to investigate whether increased BPA exposure by consuming canned beverage actually affect cardiovascular indices and epigenetic feature.
• For this aim, the investigators will conduct a cross-over trial.

Inclusion Criteria:

• Reside in Seoul
• Who provided Informed consent

Exclusion Criteria:

• Who has cancer
• Who has disease or disorder of liver, nervous system, endocrine system, cardiovascular system
• Who does not provieded informed consent