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Endocrine disruptors are known as a cancer cause. On pregnant women, it can induce major foetal pathology and impact growth.
Among those molecules, bisphenol-A (BPA) is a plasticizer that can be found on cans and water.
Through a prevention program, the investigators tried to warned pregnant women on endocrine disruptors exposition risks. The goal here is to assess the effectiveness of this program on their fresh products consumption.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Leaflet only | No Intervention | Women will only receive a leaflet about endocrine disruptor at home. | |
| non immersive program | Active Comparator | In addition of the leaflet, women will sit in the sensibilisation program that will take place in a neutral environment |
|
| immersive program | Experimental | In addition of the leaflet, women will si in the sensibilisation program that will take place in an immersive environment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sensibilisation program "Ma maison, mon environnement santé" | Behavioral | The aim of this program is to spread the awarness about endocrine disruptors through workshops and presentation. |
| Measure | Description | Time Frame |
|---|---|---|
| program effectivness | Assessing the Effectiveness of the Prevention Program "My Home, My Health Environment" (consists of a series of workshop in the second and third trimesters of pregnancy) in an immersive environment or not, to evaluate the consumption of fresh products according to exposure endocrine disruptors (cans or industrial products). | During the pregnancy (second and third trimester) |
| Measure | Description | Time Frame |
|---|---|---|
| psychosocial aspects | Assess if the program impact any psychosocial aspects, this outcome will be determine with a psychosocial questionary (to do before and after the intervention for compare the results) | During the pregnancy (second and third trimester) |
| Urine concentration |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Universitaire de Poitiers | Poitiers | 86000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41361687 | Derived | Robalo M, Ayraud-Thevenot S, Migeot V, Gourgues AS, Albouy M, Venisse N. Detection of Endocrine Disruptors in Human Placenta: A Pilot Study on Exposure and Histopathological Findings. Ther Drug Monit. 2026 Apr 1;48(2):258-265. doi: 10.1097/FTD.0000000000001414. Epub 2025 Dec 9. | |
| 34863252 | Derived | Ouazzani HE, Rouillon S, Venisse N, Sifer-Riviere L, Dupuis A, Cambien G, Ayraud-Thevenot S, Gourgues AS, Pierre-Eugene P, Pierre F, Rabouan S; DisProSE Group; Migeot V, Albouy-Llaty M. Impact of perinatal environmental health education intervention on exposure to endocrine disruptors during pregnancy-PREVED study: study protocol for a randomized controlled trial. Trials. 2021 Dec 4;22(1):876. doi: 10.1186/s13063-021-05813-5. |
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Assess if the program has an impact on the urinary endocrine disruptors's concentrations, this outcome will be determine with samples of urine (to do before and after the intervention for comparate the results) |
| During the pregnancy (second and third trimester) |
| Milk concentration | Assess the milk endocrine disruptors's concentration difference between women exposed and unexposed to the program | After the birth of the child (first year) |
| foetal growth | Study the relation between endocrine disruptors expositions and foetal growth by merging PREVED and EDDS (a previous trial) datas. | After the birth of the child (first year) |