The Interaction Between Appetite Hormones

The Interaction Between Appetite Hormones and Their Importance for Maintenance of Weight Loss After a Low Calorie Diet

Glucagon Like Peptide (GLP) -1 affects metabolic response corrected for weight change

Many obese people have had several successful weight losses, however very few can maintain the weight loss over a longer period (e.g. one year) Therefore, we want to investigate the metabolic response and the importance for maintenance of weight loss in obese people, who lost at least 7, 5 % body weight by low calorie diet followed by 52 weeks of diet weight maintenance with or without supplement of GLP-1.

Inclusion Criteria:

• BMI > 30 and < 40 (kg/m2)
• Healthy

Exclusion Criteria:

• Other known illness
• Medicine that affects glucose- and lipid metabolism, appetite or food intake
• Pregnancy
• Breast feeding