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The purpose of this cross over pilot study is to investigate the urinary catabolites of Proanthocyanidines (PACs) as biomarkers of cranberry extracts in healthy young women.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cranberry extract 1 | Experimental | One capsule with a proanthocyanidin standardized cranberry extract of 36 mg and one capsule of placebo cranberry extract. |
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| cranberry extract 2. | Experimental | Two capsules with a proanthocyanidin standardized cranberry extract of 36 mg. |
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| cranberry extract 3. | Placebo Comparator | Two capsules with a proanthocyanidin standardized cranberry extract of 2 mg. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cranberry extract | Dietary Supplement | The aim of this pilot study is to evaluate the urinary catabolites of PACs as a biomarker of consumption of cranberry extracts within 9 hours of intercourse. Once a week, for 3 weeks, the women will receive a sequence of 3 different cranberry extracts (72 mg, 36 mg and 2mg (placebo)). The participant will have to collect its urine for a period of 9 hours in 3 different containers (one different container for 3 hours). |
| Measure | Description | Time Frame |
|---|---|---|
| Urinary catabolites of PACs | within 9 hours following the intake of cranberry extracts |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sylvie Dodin, MD | Laval University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laval University, Department of Medecine, Institut sur la nutrition et les aliments fonctionnels (INAF). | Québec | Quebec | G1V 0A6 | Canada |
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| ID | Term |
|---|---|
| D014552 | Urinary Tract Infections |
| ID | Term |
|---|---|
| D007239 | Infections |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |