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The objective of this study is to assess the changes in daily physical activity and gait pattern, following a viscosupplement injection among a population who is suffering from hip osteoarthritis. A kinetic and kinematic gait analysis, an Actigraph activity monitor, a functional Timed-Stair-Test and two questionnaires (Medical Outcome Study Short-Form36 (MOS-SF36), Hip disability and Osteoarthritis Outcome Score (HOOS)) about how the pathology affects the quality of life, will be use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hyaluronan | Experimental | Hyaluronan acid Neovisc : one 6cc (viscosupplement) intra-articular injection |
|
| Bupivacaine | Placebo Comparator | one Marcain extra-capsular injection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hyaluronan | Drug | Intra-articular injection |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in hip flexion-extension range of motion | Subtraction between maximum and minimum flexion measured with motion capture system during gait | Change from Baseline at 6 months |
| Change in daily physical activity | Intensity and duration of the daily physical activity measured with pedometer | Change from Baseline at 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in hip pain | Questionnaires HOOS | change from Baseline at 6 months |
| Change in quality of life | Questionnaires: MOS-SF36 and HOOS |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Antoine Cantin-Warren, B.Sc. | Laval University | Principal Investigator |
| Étienne L. Belzile, MD | Laval University | Study Director |
| Philippe Corbeil, Ph.D. | Laval University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pavillon de l'Éducation Physique et des Sports - Université Laval | Québec | G1V 0A6 | Canada |
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| ID | Term |
|---|---|
| D015207 | Osteoarthritis, Hip |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D006820 | Hyaluronic Acid |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D006025 | Glycosaminoglycans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
| D000813 | Anilides |
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| Bupivacaine | Drug | Extra-capsular injection |
|
|
| Change from Baseline at 6 months |
| Change in walking cadence | Measured during 3D gait analysis | Change from Baseline at 6 months |
| D012216 |
| Rheumatic Diseases |
| D000577 |
| Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |