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The purpose of this study is to determine whether moxibustion is effective to mild and moderate ulcerative colitis and the effect of moxibustion on metabolism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| moxibustion group | Experimental | herb-partitioned moxibustion on bilateral Tianshu (ST25) and Shangjuxu (ST37) |
|
| bran-partitioned moxibustion | Placebo Comparator | bran-partitioned moxibustion on bilateral Tianshu (ST25) and Shangjuxu (ST37) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| herb-partitioned moxibustion | Other | Ignited moxa cones are placed upon herbal cake. Herbs are smashed into powder. Every 2.8g medicine powder mix with 3g millet wine and then be pressed into herbal cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the herbal cake with a moxa cone will be fixed on Tianshu and Shangjuxu. |
| Measure | Description | Time Frame |
|---|---|---|
| disease activity index (DAI) | Using Mayo subscore | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Inflammatory Bowel Disease Questionnaire (IBDQ) | 3 months | |
| symptom score | 3 months | |
| histomorphology observation of intestinal mucosa |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Huangan Wu, Doctor | Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai University of Traditional Chinese Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Institute of Acupuncture-Moxibustion and Meridian | Shanghai | 200030 | China |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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|
| bran-partitioned moxibustion | Other | Ignited moxa cones are placed upon bran cake. Every 2.8g bran powder mix with 3g millet wine and then be pressed into bran cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the bran cake with a moxa cone will be fixed on Tianshu and Shangjuxu. |
|
Using the Geboes histology score |
| 3 months |
| metabolic profile of intestinal mucosa, urine, plasma and serum | 3 months |
| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |