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| ID | Type | Description | Link |
|---|---|---|---|
| BCMC13AH06 | Other Identifier | Bucheon St Marys' Hospital, The Catholic University of Korea |
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Stroke patients with dysphagia have restrictive lung dysfunction and impaired cough response. This pilot study was performed to determine if Mechanical Insufflation Exsufflation (MIE) therapy can help recover impaired cough function.
Mechanical Insufflation- Exsufflation (MI-E) is an assisted coughing machine that has been proven to be very effective in preventing the deterioration of pulmonary function in patients with degenerative neuromuscular disorders. Impaired airway clearance in stroke patients is associated with increased incidence of aspiration pneumonia.
In this pilot study the investigators attempt to assess the efficacy of MI-E as part of a protocol for patients with dysphagia with impaired cough response.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mechanical insufflation exsufflation | Active Comparator | Application of cough assist machine as part of the regular physiotherapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mechanical Insufflation Exsufflation | Device | Mechanical Insufflation Exsufflation -Each patient received daily treatments by means of a light-weight, elastic oronasal mask. Treatments were divided between morning and afternoon and were carried out 5 times a week. A total of 20 sessions were carried out by a a trained respiratory therapist. |
| Measure | Description | Time Frame |
|---|---|---|
| Coughing force as assessed by peak cough flow meter | baseline, 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Maximal inspiratory and expiratory pressure | baseline- 2 weeks | |
| Cough force during reflexive cough test | baseline, 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of pneumonia | baseline 2 weeks |
Inclusion criteria Presence of neurogenic dysphagia Presence of impaired cough function
Exclusion criteria Episodes of acute pneumonia or diagnosis of pulmonary embolism at time of enrollment.
Previous history of chronic respiratory dysfunction or other systemic disorders that may impair respiratory function (ex,rheumatoid arthritis, chronic renal disorder, spinal cord injury) Episodes of diaphragm weakness due to peripheral polyneuropathy or phrenic nerve injury Concomitant diagnosis of myopathy, muscular dystrophy, or other neurodegenerative disorders.
Episodes of rib fracture within one year of enrollment. Chronic alcoholism Diagnosis of bullous emphysema Diagnosis of chronic renal failure
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| Name | Affiliation | Role |
|---|---|---|
| Sun Im | The Catholic University of Korea | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bucheon St Mary's Hospital | Bucheon-si | South Korea |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D003680 | Deglutition Disorders |
| D003371 | Cough |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |