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Stroke is a debilitating condition that can impair multiple functions, including swallowing. Stroke patients with dysphagia, are known to have reduced cough due to multiple mechanisms and this can impair their expectorate function. This can lead to accumulation of sputum and mucoid, ultimately resulting in aspiration pneumonia. Stroke patients, especially those with dysphagia, are also known to have expiratory muscle weakness and weak cough than healthy controls. Stroke patients are also known to have reduced diaphragm movement than healthy subjects. Sonography is a useful tool that can easily and reliability measure diaphragm movement. Whether stroke patients with dysphagia have reduced diaphragm movement than those without dysphagia and whether this affects voluntary cough have not been reported yet.
This study attempts to evaluate diaphragm movements during voluntary cough in stroke patients with dysphagia and determine whether this reduced diaphragm movement correlates to their peak flow meters during voluntary cough.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stroke patients with dysphagia | Stroke patients with confirmed evidence of aspiration and severe dysphagia tha would require modified diet or nasogastric tube feeding | ||
| Stroke patients without dysphagia | Stroke patients but with no gross evidence of dysphagia or with mild dysphagia with a Penetration aspiration scale of less than 4 | ||
| healthy volunteer group | healthy volunteers with no prior history of dysphagia or stroke and who are not included in the exclusion criteria |
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| Measure | Description | Time Frame |
|---|---|---|
| Diaphragm movement during coughing | Diaphragm movement during voluntary coughing will be recorded by musculoskeletal sonogrpahy | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Maximal inspiratory and expiratory pressure | respiratory pressure meter would be used to measure inspiratory and expiratory strength | 1 day |
| Pulmonary Function test | FVC, FEV1, FEF 25-75%, FVC/FEV1 ( % ), Peak cough flow |
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Inclusion Criteria:
Exclusion Criteria:
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Stroke patients from a university affiliated medical center
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| Name | Affiliation | Role |
|---|---|---|
| Sun Im, MD, PhD | Department of Rehabilitation Medicine, Bucheon St Mary's Hospital, Catholic University of Korea, College of medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bucheon St Mary's Hospital, Catholic University of Korea | Bucheon-si | Gyenoggido | 420-717 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25234476 | Derived | Park GY, Kim SR, Kim YW, Jo KW, Lee EJ, Kim YM, Im S. Decreased diaphragm excursion in stroke patients with dysphagia as assessed by M-mode sonography. Arch Phys Med Rehabil. 2015 Jan;96(1):114-21. doi: 10.1016/j.apmr.2014.08.019. Epub 2014 Sep 16. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D003371 | Cough |
| D003680 | Deglutition Disorders |
| D053120 | Respiratory Aspiration |
| D003643 | Death |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| 1 day |
| Motricity index | Baseline |
| Canadian Neurological Stroke Scale | Baseline |
| Diaphragm movement during inspiration | Diaphragm movement will be recorded after deep inspiration | 1 day |
| Diaphragm movement during expiration | Diaphragm movement during expiration will be recorded | 1 day |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D010335 | Pathologic Processes |