Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey. Enrolled patients will have coronary CT, 2D echocardiogram, treadmill test, pulse wave velocity, augmentation index, carotid intima-media thickness, and abdominal fat mass evaluation. Moreover, lipid profiles and inflammatory markers such as hsCRP, IL-6, TNF-alpha, VCAM-1, ICAM-1, adiponectin, MMP-9 will be measured. All participants will repeat the test and survey every year in Korea University Hospital.

Inclusion Criteria: 3 out of 5 criteria

• Central obesity: Men ≥ 90 cm Women ≥ 85 cm
• Plasma triglycerides ≥ 150 mg/dL
• HDL cholesterol Men < 40 mg/dL, Women < 50 mg/dL
• Blood pressure ≥130/85 mm Hg (or treatment for hypertension)
• Fasting plasma glucose ≥ 100 mg/dL
• Age between 30 to 64
• Consent to our registry protocol

Exclusion Criteria:

• Patients who could not undergo coronary CT, 2D echocardiogram, treadmill test, and pulse wave velocity.

Patients with metabolic syndrome living in Seoul area