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| Name | Class |
|---|---|
| Örestadskliniken | OTHER |
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This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care. Special emphasize is to correlate biomarkers to different phases of COPD, to progression of the disease, and to treatment of the disease. Furthermore, linkage between COPD, cardiovascular disease, and lung cancer will be investigated by identifying protein biomarkers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GOLD stage I | |||
| GOLD Stage II | |||
| GOLD Stage III | |||
| GOLD Stage IV | |||
| Smokers/ex-smokers w/o COPD | |||
| non-Smokers w/o COPD |
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| Measure | Description | Time Frame |
|---|---|---|
| Advanced disease etiology requiring hospitalization. | 2 years |
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Inclusion Criteria:
Diagnosed with COPD Gold stage 0-IV
Exclusion Criteria:
Patients with inflammatory diseases Patients with cancer Patients using immune system regulating drugs
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Primary care clinic in Malmö, Sweden
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| Name | Affiliation | Role |
|---|---|---|
| Johan Malm | Clincal Chemistry, Lund University | Study Chair |
| György Marko-Varga | Clinical Protein Science & Imaging, Lund University | Principal Investigator |
| Mikael Truedsson | Örestadskliniken Malmö | Principal Investigator |
| Elisabet Wieslander | Division of Oncology and Pathology, Lund University | Principal Investigator |
| Thomas E Fehniger | Clinical Protein Science & Imaging, Lund University | Principal Investigator |
| Magnus Dahlbäck | Clinical Protein Science & Imaging, Lund University | Principal Investigator |
| Roger Appelqvist | Clinical Protein Science & Imaging, Lund University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Örestadskliniken | Malmö | Sweden |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D002318 | Cardiovascular Diseases |
| D008175 | Lung Neoplasms |
| D012907 | Smoking |
| D016540 | Smoking Cessation |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001519 | Behavior |
| D015438 | Health Behavior |