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The main objective of this study is to evaluate Beta cells in patients with a neonotal diabetes linked to a genetic abnormality Metabolic caracteristics will described using a transversal cohort study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adult with neonatal diabetes | Adult with neonatal diabetes (before 1 year ) and need for insulin | ||
| non diabetic adults with a relative with neonatal diabetes |
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| Measure | Description | Time Frame |
|---|---|---|
| Mean insulin secretion output | Week after inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| insulin secretion outout after arginine perfusion | during hospitalisation (3 days) | |
| sensitivity to insulin | during hospitalisation (3 days) | |
| glucago secretion output |
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Inclusion Criteria:
Exclusion Criteria:
Diabète induit (médicaments - ex corticoïdes) ou syndromique
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diabetic people
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital Siant-louis | Paris | 75010 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32273272 | Derived | Le Bourgeois F, Beltrand J, Baz B, Julla JB, Riveline JP, Simon A, Flechtner I, Ait Djoudi M, Fauret-Amsellem AL, Vial Y, Scharfmann R, Sommet J, Boudou P, Cave H, Polak M, Gautier JF, Busiah K; TNDM Long-Term Follow-Up Study Group. Long-term Metabolic and Socioeducational Outcomes of Transient Neonatal Diabetes: A Longitudinal and Cross-sectional Study. Diabetes Care. 2020 Jun;43(6):1191-1199. doi: 10.2337/dc19-0324. Epub 2020 Apr 9. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| during hospitalisation (3 days) |