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| Name | Class |
|---|---|
| University of Oslo | OTHER |
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This study examines the effectiveness of an herbal mouthwash made from salvia in maintaining good oral health among patients in palliative care. It is hypothesized that using the mouthwash made from salvia will result in better oral health and more oral comfort than using with conventional normal saline mouthwash.
The aim of this study is to examine the effectiveness of an herbal mouthwash made from salvia officinalis (SO) in maintaining good oral health among patients in palliative care. The study compares a mouthwash based on salvia tea solution with conventional normal saline mouthwash and addresses the following research questions:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Salvia | Experimental | Salvia mouthwash used 4 times per day for 4 days |
|
| Saline | Active Comparator | Saline mouthwash used 4 times per day for 4 days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Saline mouthwash | Other |
| ||
| Salvia mouthwash |
| Measure | Description | Time Frame |
|---|---|---|
| Oral health (OMAS) | Oral Mucositis Assessment Scale (OMAS) | after 4 days of using mouthwash |
| Patient's perception of oral comfort | Questions regarding oral discomfort and EORTC-OH17 | after 4 days of using mouthwash |
| Oral health (clinical evaluation) | Clinical evaluation by dentist | after 4 days of using mouthwash |
| Measure | Description | Time Frame |
|---|---|---|
| General symptom experience | Edmonton Symptom Assessment System (ESAS) | after 4 days of using mouthwash |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Anners Lerdal, PhD | Lovisenberg Diakonale Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lovisenberg Hospice | Oslo | 0440 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37072843 | Derived | Monsen RE, Kristoffersen AK, Gay CL, Herlofson BB, Fjeld KG, Hove LH, Nordgarden H, Tollisen A, Lerdal A, Enersen M. Identification and susceptibility testing of oral candidiasis in advanced cancer patients. BMC Oral Health. 2023 Apr 18;23(1):223. doi: 10.1186/s12903-023-02950-y. | |
| 33586003 | Derived | Monsen RE, Herlofson BB, Gay C, Fjeld KG, Hove LH, Malterud KE, Saghaug E, Slaaen J, Sundal T, Tollisen A, Lerdal A. A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial. Support Care Cancer. 2021 Sep;29(9):4997-5007. doi: 10.1007/s00520-021-06021-2. Epub 2021 Feb 14. |
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| ID | Term |
|---|---|
| D014987 | Xerostomia |
| D019226 | Oral Ulcer |
| ID | Term |
|---|---|
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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