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The purpose of this study was to compare the anesthetic efficacy of articaine, lidocaine and mepivacaine in patients with irreversible pulpitis of mandibular molar.
Conventional inferior alveolar nerve block (IANB) is the most commonly used technique for achieving pulpal anesthesia in posterior mandibular endodontic procedures. However, IANB has a high failure rate and success rates are even lower when applied for the treatment of mandibular posterior teeth with irreversible pulpitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| lidocaine | Experimental | injections of 3.6 mL of 2% lidocaine with 1:100,000 epinephrine Intervention: inferior alveolar nerve block injection |
|
| mepivacaine | Experimental | injections of 3.6 mL of 2% mepivacaine with 1:100,000 epinephrine Intervention: inferior alveolar nerve block injection |
|
| articaine | Experimental | injections of 3.6 mL of 4% articaine with 1:100,000 epinephrine Intervention: inferior alveolar nerve block injection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention: inferior alveolar nerve block injection | Drug | -22 patients received inferior alveolar nerve block injections of 3.6 mL (equivalent to 2 cartridges) |
|
| Measure | Description | Time Frame |
|---|---|---|
| pulpal anesthesia | pulpal anesthesia was tested with an electric pulp stimulator | Ten minutes after the inferior alveolar nerve block |
| Measure | Description | Time Frame |
|---|---|---|
| analgesia | To evaluate the intensity of pain during the pulpectomy a verbal analogic scale was adopted | the patients were instructed to report any painful sensation at three phases: 1) dentin 2) pulp chamber 3) root canal |
| Measure | Description | Time Frame |
|---|---|---|
| lip anesthesia | The investigators evaluated the subjective lip anethesia by asking the patient whether his/her lip was numb | ten minutes after the inferior alveolar nerve block |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Isabel P Tortamano, PhD | USão Paulo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emergency Center of the School of Dentistry at the University of São Paulo | São Paulo | São Paulo | 05508-900 | Brazil |
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