Ketamine and Changes of the Short Portable Mental Status Questionnaire

Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.

- Cognitive changes are related to aging, affecting the performance of older patients in the solution of problems and the execution of tasks.

This phenomenon has been observed as a decline of neurophysiological domains, especially memory, and the velocity of thought.

• Anesthesia and surgery performed contributes to its development then, is named post-operative cognitive dysfunction (POCD). The incidence varies due to conditions of:

  1. Anesthesia and surgery.
  2. The time elapsed after surgery.
  3. The population studied, and the type of cognitive test employed.

• The aim of this study is to evaluate the changes around the Short Portable Mental Status Questionnaire (SPMSQ-E) after ketamine administration on ophthalmic surgery on the common conditions of geriatric patients, -comorbid and settings as minor surgery-.

Participants will be patients programmed for a vitrectomy or cataract surgery involving a retrobulbar block, to be carried out with a local anesthesia.

- Administration of ketamine will be suspended during the study for any cause considered as a risk to the patient according to the judgment of the researchers.

Inclusion Criteria:

• Patients be over 60 years and older.
• Intraocular pressure less than 20 millimeter of mercury.
• American Society of Anaesthesiologists (ASA) physical status classification, I-III.

Exclusion Criteria:

• History of psychosis or schizophrenia.
• Nephropathy.
• Difficult to control hypertension.
• Uncontrolled hepatic disorders.
• Allergy to ketamine.
• Moderate to severe depression.
• Post-operative delirium.
• Needed to use medications other than those contemplated in the study.