The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery

The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery

The purpose of this study is to analyze the Ketamine with its anti-inflammatory profile would be able to prevent cognitive disorders in the postoperative period of cardiac surgery, since these disorders contribute to an impact on morbidity / mortality in this population.

Inclusion Criteria:

• Patients aged over 50 years.
• Be submitted to cardiac surgery by sternotomy and with the use of cardiopulmonary bypass (CPB).
• American Society of Anesthesiologists classification 1, 2,3 and 4.

Exclusion Criteria:

• Patients undergoing reoperation.
• Patients undergoing heart transplantation.
• Patients using vasopressor agents and / or ionotropic continuous preoperatively.
• Patients with prior endotracheal intubation and consequently Ventilatory Assistance Mechanics.
• Patients with documented psychiatric disorders.
• Patients with previous cognitive disorders.
• Patients with a history of alcohol or drug abuse.
• Patients with a history of cerebrovascular accident (CVA) with less than 3 months.