Evaluation of Nutritional Status and Fatigue in Patients With Multiple Sclerosis

Evaluation of the Nutritional Status of Patients With Multiple Sclerosis and Relationship With Fatigue

Multiple sclerosis (MS) is a chronic progressive neurological disease, the leading cause of disability after injury accidents in young adults. Among the many symptoms, fatigue is very common with a significant impact on quality of life. Also, the disability caused by multiple sclerosis can alter food intake and can cause nutritional deficiencies. Nutrients such as proteins, minerals (iron, calcium, magnesium), some vitamins (B12, 25 OHD) are often deficient in this population with consequences in physical performance such as endurance and muscle strength. We propose to study the link between fatigue and shortcomings encountered in a defined population of MS patients.

Inclusion Criteria:

• Patients between 18 and 65 years old
• Expended disability status scale (EDSS) between 0 and 7
• Diagnosis of MS according to the revised criteria of McDonald
• Clinically stable patients in the past 3 months
• Coverage of the social insurance
• Informed consent to participate

Exclusion Criteria:

• Cognitive disorders that can hinder answering questionnaires
• Presence of uncontrolled metabolic disease(s)
• Malabsorption
• Patients with a gastrostomy
• Active cancer under treatment
• Anorexia
• Pregnancy or breast feeding
• Severe psychiatric disorder(s)
• No informed consent to participate
• No coverage by the social insurance