Study of the Effect of the Cognitive Orientation to Daily Occupational Performance (CO-OP) on Cognitive Impairment in Parkinson's Disease

Determining the Applicability of the Cognitive Orientation to Daily Occupational Performance (CO-OP) as a Meta-Cognitive Rehabilitation Strategy for Individuals With Parkinson's Disease-Related Cognitive Impairment

The purpose of the study will be to determine the effects of the Cognitive Orientation to daily Occupational Performance (CO-OP) as a treatment program for individuals with Parkinson's disease-related cognitive impairment. The potential effects of the CO-OP on successful engagement in meaningful activities will be examined from participants' and live-in caregivers' perspectives. Effects of the CO-OP on participant-perceived health-related quality of life and caregiver burden will also be evaluated.

Hypotheses:

1. Training with the CO-OP will have an effect or multiple effects on participation in meaningful activities and health-related quality of life for individuals with Parkinson's-related cognitive impairment.
2. Training with the CO-OP will have an effect or multiple effects on caregiver burden and health-related quality of life for caregivers of individuals with Parkinson's-related cognitive impairment.

Inclusion Criteria for Participants with Parkinson's disease:

• Clinical diagnosis of Idiopathic Parkinson's Disease
• Presence of a live-in caregiver or significant other who is willing to participate in the study
• Montreal Cognitive Assessment (MoCA) score above 16/30 and below 26/30
• Schwab and England Activities of Daily Living Scale scores between 60% and 90%
• Hoehn and Yahr Scale scores between Stage 1 and Stage 3
• Self-reported difficulty completing routine functional activities that may be related to new cognitive changes since PD diagnosis

Exclusion Criteria for Participants with Parkinson's disease:

• Clinical diagnosis of atypical parkinsonism
• Clinical diagnosis of young-onset Parkinson's disease
• Co-morbidities associated with cognitive impairment
• Poorly controlled depression
• Clinical diagnosis of dementia
• Residence outside boundaries of the city of Winnipeg, Manitoba, Canada

Inclusion Criteria for Caregiver Participants:

• Live in the same residence as participant with Parkinson's
• Be willing to participate

Exclusion Criteria for Caregiver Participants:

• Scores at or below 16/30 on Montreal Cognitive Assessment (MoCA)