Gut Hormone Response After Paleolithic-type Meals

Gut Hormone Response After Two Paleolithic-type Meals Compared to a Modern-type Meal Composed According to WHO Guidelines

The effects of two palaeolithic-type meals will be assessed with respect to a panel of gut hormones, satiety, blood glucose and insulin levels as compared to a meal constructed along the lines of the world Health Organisation dietary recommendations

In the current study the effects of two palaeolithic-type meals will be assessed with respect to a panel of gut hormones (including incretins), satiety, blood glucose and insulin levels.

Inclusion Criteria:

• Body Mass Index (BMI) 18-27 inclusive
• Apparently healthy: no medical conditions which might affect study measurements as judged by Leatherhead physician based on a health questionnaire)
• Having general practitioner
• Reported dietary habits: no medically prescribed diet, no slimming diet, used to eat 3 meals a day, no vegetarian
• Reported intense sporting activities less than 10h/w
• Reported alcohol consumption less than 21units/w
• non-smoking
• A fasting capillary blood glucose value within the local normal reference value: 4-6.5 mmol/L measured by finger prick

Exclusion Criteria:

• Use of medication which interferes with the study measurements (as judged by the study physician)
• Being an employee of Unilever or Leatherhead Food Research
• Scoff questionaire score ≥ 2
• Eating habit questionnaire ≥ 14
• Smoking
• Dislike, allergy or intolerance t the test meals or the ad libitum meal
• Reported participation in another nutritional or biomedical trial 3 months before pre-study examination or during the study
• Reported participation in night shift work two weeks prior to the pre-study investigation during the study. Night work is defined as working between midnight and 06.00 AM