Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain

Phase 3 Study Comparing Transversus Abdominis Plane Block After Caesarian Section Usin Bupivacaine 0.5% vs. Bupivacaine 0.25% vs. Placebo (Normal Saline).

Adding TAP block with Bupivacaine may decrease the use of PCA bolus use after caesarean section for pain relief.

Participants in the study will be randomized to TAP block with 0.5% or 0.25% bupivacaine or with placebo (normal saline).

The number of PCA bolus used within 24 hours post cesarean section will be compared between the groups.

Inclusion Criteria:

Healthy pregnant (ASA II) patients presenting for planned Cesarean delivery at New York Methodist Hospital under combined spinal epidural anesthesia

Exclusion Criteria:

• They are unable or are unwilling to take part in the study
• They have a history of allergy to any of the medications to be used in the study
• They have a history of drug abuse or chronic pain or opioid use
• They weigh less than 60kg
• They have a multiple gestation, placental disease, preeclampsia other disease of pregnancy
• They have a contraindication to neuraxial anesthesia (i.e., bleeding problems, bacteremia, etc.)
• They are unable to understand instructions or questions related to the study
• ASA III or IV