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The purpose of this research study is to evaluate whether or not adding a Transversus Abdominis Plane Block (TAP block) improves pain control for patients having a cesarean section. A TAP block is a type of nerve block where at the end of the surgery an injection of a long acting local anesthetic is made into the abdominal wall. In studies in patient's having other abdominal surgeries this has reduced the amount of narcotics patients need for pain control. This may also led to patients being more active after surgery and maybe spending less time in hospital.
Randomized clinical trial of Transversus Abdominis Plane Block (TAP block) at Cesarean Section.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgeon-administered Transversus Abdominis Plane Block (TAP block) | Experimental | After uterine closure, the anterior abdominal wall on the contralateral side to the surgeon is elevated and retracted laterally by an assistant. The bowel and uterus is retracted using the surgeon's non-dominant hand, with or without a sponge. Under direct visualization, a blunted spinal needle is inserted lateral to the rectus muscle to avoid injury to inferior epigastric blood vessels. The needle is then gently advanced through the transversus abdominis fascia into the TAP plane, identified at loss of resistance, or 'a pop'. After aspiration to confirm no accidental placement of the needle intravascularly, local anaesthetic is infiltrated into the transverse abdominis plane through the parietal peritoneum by the surgeon at a prespecified dose of 0.25% bupivicaine 0.25 mL/kg (approximately 20cc). This is repeated on the contralateral side, after which closure of the fascia, subcutaneous tissue, and skin were performed. |
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| No TAP block | No Intervention | A sham procedure will not be performed but the patient will be unaware of whether or not an injection was done. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Surgeon-administered Transversus Abdominis Plane Block 0.25% bupivicaine 0.25 mL/kg | Other | Surgeon-administered Transversus Abdominis Plane Block |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post operative Pain | VAS scale 0-no pain to 10-worst pain | 12 hours post op |
| Measure | Description | Time Frame |
|---|---|---|
| Time to first request for rescue analgesia in hours | Time from completion of surgery to first request for rescue analgesia in hours | 48 hours post op |
| Post operative Opioid use | Total opioid consumption in the first 24h and 48h mark, postoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stephen Wood, MD | Contact | 4039441438 | slwood@ucalgary.ca |
| Name | Affiliation | Role |
|---|---|---|
| Stephen Wood, MD | University of Calgary | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Calgary | Recruiting | Calgary | Alberta | T2N 2T9 | Canada |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Apr 12, 2024 |
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|
| up to 48 hours post op. |
| Time from surgery to discharge from hospital | Time from completion of surgery to discharge | Up to discharge from hospital, usually 1-3 days |
| Mar 6, 2025 |
| Prot_SAP_000.pdf |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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