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| ID | Type | Description | Link |
|---|---|---|---|
| 268011 | Other Grant/Funding Number | Grant Agency of Charles University in Prague |
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Breast-conserving treatment (BCT) leads to a progressive and deteriorating breast deformity. Fatgrafting is ideal for breast reconstruction after BCT. The most frequently utilized technique for fat processing is centrifugation. The PureGraft device (Cytori Therapeutics, USA) is a new method that involves washing and filtering the fat to prepare the graft. The investigators compared the subjective and objective outcomes of two fat-processing methods, centrifugation and PureGraft filtration.
Thirty patients underwent breast reconstruction performed by a single surgeon (OM) after BCT in our department between April 2011 and September 2012. The patients were preoperatively divided into two groups randomly: 15 received fatgrafts processed by centrifugation, and 15 received fatgrafts processed by washing in PureGraft bags. The patients were followed up for 12-30 months.To measure the subjective outcome, the investigators distributed the BREAST-Q questionnaire to all the patients both preoperatively and one year postoperatively. The BCCT.core software evaluated the objective outcome of breast reconstruction by fatgrafting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Centrifugation | Active Comparator | Patients recieved fatgraft processed by Centrifugation |
|
| Puregraft | Active Comparator | Patients recieved fatgraft processed by Puregraft |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Puregraft | Other |
| ||
| Centrifugation |
| Measure | Description | Time Frame |
|---|---|---|
| Outcomes after centrifugation versus PureGraft for fatgrafting to the breast after breast-conserving therapy | 1 year |
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Inclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ondrej Mestak, M.D. | Charles University, Czech Republic | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bulovka Hospital | Prague | 180 00 | Czechia |
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| ID | Term |
|---|---|
| D002498 | Centrifugation |
| ID | Term |
|---|---|
| D008919 | Investigative Techniques |
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