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| ID | Type | Description | Link |
|---|---|---|---|
| 08431910200 | Other Grant/Funding Number | Shanghai Municipal Science and Technology Commission |
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The purpose of this study is to prove whether general anesthesia combined with epidural anesthesia could better maintain body balance of Th1/Th2 and Treg/Th17 compared with general anesthesia, so as to reduce the surgical stress-related immunosuppression, and to improve the prognosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| general anesthesia & epidural anesthesia | Experimental | 26 patients received general anesthesia combined with epidural anesthesia for surgery, and patient-controlled epidural analgesia for 2 days after surgery |
|
| general anesthesia | Experimental | 27 patients received general anesthesia for surgery, and patient-controlled intravenous analgesia for 2 days after surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| epidural anesthesia | Procedure |
| ||
| general anesthesia |
| Measure | Description | Time Frame |
|---|---|---|
| The changes of peripheral immune cells and cytokines | The changes of peripheral subtype of T-helper, myeloid-derived suppressor cells(MDSCs) and cytokines | within the first 5 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhong Shan Hospital Fudan University | Shanghai | Shanghai Municipality | 200032 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23437162 | Background | Chen WK, Miao CH. The effect of anesthetic technique on survival in human cancers: a meta-analysis of retrospective and prospective studies. PLoS One. 2013;8(2):e56540. doi: 10.1371/journal.pone.0056540. Epub 2013 Feb 20. |
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| Procedure |
Patients received general anesthesia for surgery |
|
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
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| ID | Term |
|---|---|
| D000767 | Anesthesia, Epidural |
| D000768 | Anesthesia, General |
| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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