Sevoflurane Protective Effect on Ischemia Reperfusion Injury in Microvascular Surgery

This study aimed to evaluate the possible protective effect of anesthetic technique balanced (BAL) compared to total intravenous anesthetic technique (TIVA-TCI) in ischemia reperfusion injury in microvascular flap in plastic surgery. The investigators will evaluate the viability of the flap using tissue oximetry monitoring and the level of biochemical markers in a circle at the end of the intervention.

Inclusion Criteria:

• age > 18 yr
• ASA (American Society of Anesthesiology) I-II

Exclusion Criteria:

• Known unusual reaction to anesthetic drugs
• Evaluation of anesthesia increased risk for malignant hyperthermia.
• History of vascular disease.
• History of bleeding diathesis.
• Tabagism