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| Name | Class |
|---|---|
| Johnson & Johnson Medical Companies | INDUSTRY |
Surgery is the first standard treatment for stomach cancer, but it still has negative factors such as bleeding, leakage, closure, surgery part infection and cardiovascular and lung complication by general anesthesia.
electric cautery is used extensively in surgery room due to the utility of simultaneous severance and hemostasis. In some case, the electric current from vitality electrode may unexpectedly stimulate or damage nearby muscles and nerves. Ultrasonically activated shears (UAS) is a device to transform the protein of organ for organ incision or hemostasis. General advantages possibly include shortened operating time, decrease of operative blood loss, and relatively less damages to the normal organ. UAS is commonly used in the operation room, which is now considered as a secure and useful medical device for for tissue dissection and coagulation. Also, it is expected to lower the risk of surgery by reducing operating time and blood loss.
However, clinical evidence is not sufficient for this device until now. Therefore, in this study,
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ultrasonically Activated Shear | Active Comparator | Dissection and lymphovascular sealing with Ultrasonically Activated Shears |
|
| Conventional Monopolar Electrocautery | Active Comparator | Dissection and lymphovascular sealing with Conventional Monopolar Electrocautery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasonically activated Shears | Device | Dissection and lymphovascular sealing with Ultrasonically Activated Shears |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intraoperative blood loss | within a month | |
| Amount of drain at postoperative period | within a month |
| Measure | Description | Time Frame |
|---|---|---|
| Operation time | within 2 months | |
| Transfusion | within 2 months | |
| Inflammatory factors (Serum C-Reactive Protein and cytokines, ascites cytokines) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Han-Kwang Yang, M.D., Ph.D. | Seoul National University Hospital, Seoul, Korea, Republic of. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | 82 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27613551 | Derived | Oh SY, Choi B, Lee KG, Choe HN, Lee HJ, Suh YS, Kong SH, Lee HJ, Kim WH, Yang HK. Ultrasonically Activated Shears Reduce Blood Loss without Increasing Inflammatory Reactions in Open Distal Gastrectomy for Cancer: A Randomized Controlled Study. Ann Surg Oncol. 2017 Feb;24(2):494-501. doi: 10.1245/s10434-016-5518-3. Epub 2016 Sep 9. |
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| Conventional Monopolar Electrocautery | Device | Dissection and lymphovascular sealing with Conventional Monopolar Electrocautery |
|
|
| within 2 months |
| Postoperative hospital stay | within 2 months |
| 4. Postoperative hospital stay Complications | within 2 months |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |