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| Name | Class |
|---|---|
| Fundação de Amparo à Pesquisa do Estado de São Paulo | OTHER_GOV |
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The study aimed to evaluate the chronic effects of resistance training on blood pressure and biochemical exams in hypertensive elderlies and the influence of the polymorphism of the angiotensin converting enzyme in these response.
To investigate the chronic effects of resistance training on blood pressure and biochemical exams in elderly, 135 hypertensive elderlies were divided into 2 groups: trained and control. The trained group was submitted to a resistance training period. Before the 16 weeks ACE gene was genotyped (PCR). Before and after 16 weeks, blood pressure (ambulatory), HDL-cholesterol, Total cholesterol, Glycemia, Triacylglycerol (colorimetric assay) and plasminogen activator inhibition (PAI-1), intercellular adhesion molecule (ICAM-1), vascular endothelial cell adhesion molecule (VCAM-1), Adiponectin, tumor necrosis factor alpha (TNF-alpha), C Reactive Protein, Angiotensin II, Angiotensin Converting Enzyme, Angiotensin 1-7, (ELISA assay) were measured.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Resistance training | Experimental | Resistance training performed three times at week for 16 weeks, in 8 exercises for the main muscles, the protocol of 3 sets of 10 repetitions with intensity of 50% of 1 maximum repetition (MR). |
|
| Control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Resistance training | Behavioral | Resistance training performed three times at week for 16 weeks, in 8 exercises for the main muscles, the protocol of 3 sets of 10 repetitions with intensity of 50% of 1 maximum repetition (MR). |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Pressure | Blood pressure was measured by Ambulatorial Monitoring Blood Pressure before and after 16 weeks of intervention. | 16 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| HDL-cholesterol | HDL-cholesterol was analyzed by colorimetric assay, before and after 16 weeks of intervention. | 16 weeks |
| Total Cholesterol | Total cholesterol was analyzed by colorimetric assay, before and after 16 weeks of intervention. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UNIMED | Santos | São Paulo | Brazil |
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| 16 weeks |
| Glycemia | Glycemia was analyzed by colorimetric assay, before and after 16 weeks of intervention. | 16 weeks |
| Triacylglycerol | Triacylglycerol was analyzed by colorimetric assay, before and after 16 weeks of intervention. | 16 weeks |
| PAI-1 | PAI-1 was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| ICAM-1 | ICAM-1 was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| VCAM-1 | VCAM-1 was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| Adiponectin | Adiponectin was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| TNF alpha | TNF alpha was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| C Reactive Protein | C Reactive Protein was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| Angiotensin II | Angiotensin II was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| Angiotensin Converting Enzyme | Angiotensin Converting Enzyme was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| Angiotensin 1-7 | Angiotensin 1-7 was analyzed by ELISA assay, before and after 16 weeks of intervention. | 16 weeks |
| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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