Causative Diagnosis on Prosthetic Joint Infections: Establishment of a Comprehensive Diagnostic Strategy

Causative Diagnosis on Prosthetic Joint Infections: Establishment of a Comprehensive Diagnostic Strategy

On joint orthopaedic hardware infections are one of the most frequently encountered complications in orthopaedic surgery. However 6% of the cultures remain sterile, etiological diagnosis cannot be established despite obvious signs of infection. As part of this research project, we have developed a new strategy diagnosis including directly the use of PCR to reduce the number of negative results. This should have a major therapeutic impact in terms of timeliness and specificity of antibiotic.

Primary:

Evaluate the effectiveness of the new diagnostic strategy on etiological identification of prosthesis infections.

Hypothesis:

Minimum 6 percent increase in the number of patients with an etiological diagnosis of infection on prosthesis.

Inclusion Criteria:

• Patient is more than 18 years old.
• Patient with a prescription of a microbiologic diagnostic of Prosthetic joint infection
• Patient who do not declined to have his medical records reviewed for research
• Patient with health insurance

Exclusion Criteria:

• Patient minor (<18 years).
• Pregnant or lactating woman.
• Major under guardianship Patient.
• Patient deprived of liberty or under court order