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This study is designed to evaluate the importance of the immune cells localization (distribution) between malignant tumor islets and surrounding stroma and to investigate the associations between these immune cells as well as cytokines and clinicopathological and prognostic factors of non-small cell lung cancer (NSCLC) patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lung cancer | Newly diagnosed and untreated non small cell lung cancer patients who underwent surgical resection for NSCLC (pathological stage I-III) | ||
| Control | Subjects who will have surgery due to recurrent spontaneous pneumothorax Patients without lung cancer or other malignancies |
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| Measure | Description | Time Frame |
|---|---|---|
| progression-free survival | one year after enrolment to the study |
| Measure | Description | Time Frame |
|---|---|---|
| overall survival | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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Lithuanian residents who are investigated ant treated in Hospital of Lithuanian University of Health Sciences Kaunas Clinics Department of Pulmonology and Immunology and Department of Heart, thoracic and vascular surgery
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| Name | Affiliation | Role |
|---|---|---|
| Marius Zemaitis, Assoc.Prof. | Lithuanian University of Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lithuanian University of Health Sciences | Kaunas | LT 44307 | Lithuania |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29361917 | Derived | Jackute J, Zemaitis M, Pranys D, Sitkauskiene B, Miliauskas S, Vaitkiene S, Sakalauskas R. Distribution of M1 and M2 macrophages in tumor islets and stroma in relation to prognosis of non-small cell lung cancer. BMC Immunol. 2018 Jan 24;19(1):3. doi: 10.1186/s12865-018-0241-4. |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| D009369 | Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D008171 | Lung Diseases |
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Blood serum and lung biopsy
| D012140 |
| Respiratory Tract Diseases |