Optimization of PEEP for Alveolar Recruitment in ARDS

Optimization of PEEP for Alveolar Recruitment in ARDS

Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.

Inclusion Criteria:

• ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours

Exclusion Criteria:

• less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated